The cooling coils the air comes into contact with appear to need UV-C lights on them in humid climates. That's the biggest thing. If the ducts have never been cleaned, then getting that done goes without saying. But those coils need to be cleaned, disinfected, and then UV-C light(s) installed to prevent mold & bacteria build-up in the future on them. That appears to be chiefly responsible for the dirty laundry and/or sour milk smell coming from forced-air AC systems in humid regions.
The amount of time air duct cleaning takes can depend on how extensive your duct system is, how old your air ducts are, and whether they have ever been cleaned. On average, expect a standard size home (between 2,000 and 3,000 square feet) to take 2-5 hours for one to two technicians to clean. Here are the proper protocol and equipment you should expect from a professional duct cleaning service, as recommended by the Environmental Protection Agency:
Duct cleaning generally refers to the cleaning of various heating and cooling system components of forced air systems, including the supply and return air ducts and registers, grilles and diffusers, heat exchangers heating and cooling coils, condensate drain pans (drip pans), fan motor and fan housing, and the air handling unit housing (See diagram).
Did not realize cost had gone up so much for this service. Two years ago I had furnace and ducts cleaned at my old house and it was under $400. Now the cost is $700 for this house. I will keep looking for someone to offer a lower price, check them out, and have it done. Or will find the paperwork to see who did it before. I liked this article and did learn some things. Thanks.
Air duct cleaning service providers may tell you that they need to apply chemical biocide to the inside of your ducts as a means to kill bacteria (germs) and fungi (mold) and prevent future biological growth. They may also propose the application of a "sealant" to prevent dust and dirt particles from being released into the air or to seal air leaks. You should fully understand the pros and cons of permitting application of chemical biocides or sealants. While the targeted use of chemical biocides and sealants may be appropriate under specific circumstances, research has not demonstrated their effectiveness in duct cleaning or their potential adverse health effects. No chemical biocides are currently registered by EPA for use in internally-insulated air duct systems (see Should chemical biocides be applied to the inside of air ducts?).