How exactly do you expect to kill or remove mold without it ? You can’t even clean your hvac systems coils without moisture of some type ,if you use a steam cleaner you can literally clean the whole system minus the electronics . You should do more research and possibly talk to people who do the work before posting , but don’t listen to me i only have a class A contractor license ,epa license , install /repair hvacs , rent and flip houses for a living .
If the system is sealed air-tight and a really good filtering system is in place then you should NEVER have to clean your ductwork. Most dust people see in their homes (on beds furniture etc....) is broken down insulation that is being blown into the home from the attic (venturi effect) where the duct bucket (box etc...) is not sealed at the sheetrock ceiling. On the return side, ANY leaks in the ductwork will pull hot attic air and dust into the system, clogging up everything.
How often you should clean your air ducts depends on your situation. If you or someone in the home has asthma or is acutely allergic to certain airborne materials or pollen, regular duct cleaning may be helpful. The Environmental Protection Agency doesn’t have an official position on the necessity of air duct cleaning unless the ducts have been contaminated by rodents, insects or mold, or you are aware of particles blowing out through the vents. The EPA recommends you have your air ducts cleaned on an as-needed basis. The National Air Duct Cleaners Association (NADCA) suggests having air ducts cleaned every three to five years.
If no one in your household suffers from allergies or unexplained symptoms or illnesses and if, after a visual inspection of the inside of the ducts, you see no indication that your air ducts are contaminated with large deposits of dust or mold (no musty odor or visible mold growth), having your air ducts cleaned is probably unnecessary. It is normal for the return registers to get dusty as dust-laden air is pulled through the grate. This does not indicate that your air ducts are contaminated with heavy deposits of dust or debris; the registers can be easily vacuumed or removed and cleaned.
My overall experience was pretty positive. I obviously don’t have much to say about how the technicians worked because it’s kind of hard to describe the elaborate equipment in words. What I will say though is that the cleaning had a significant impact on the freshness of the interior air. So in my opinion they got the job done, and that’s all I can ask for.
Equipment used to clean ducts varies widely. The cheaper the equipment used the more you are just wasting money. This is why it's typically not worth doing. In some situations it may be beneficial, but only after determining and investigating the duct system. This should be done by a licensed HVAC contractor and not a duct cleaner that typically do not hold and HVAC license. (Duct cleaners aren't required to be licensed in HVAC in many areas.)
Duct cleaning has never been shown to actually prevent health problems. Neither do studies conclusively demonstrate that particle (e.g., dust) levels in homes increase because of dirty air ducts. This is because much of the dirt in air ducts adheres to duct surfaces and does not necessarily enter the living space. It is important to keep in mind that dirty air ducts are only one of many possible sources of particles that are present in homes. Pollutants that enter the home both from outdoors and indoor activities such as cooking, cleaning, smoking, or just moving around can cause greater exposure to contaminants than dirty air ducts. Moreover, there is no evidence that a light amount of household dust or other particulate matter in air ducts poses any risk to your health.